Tri-Allelic Human Leukocyte Antigen (HLA) Protection Against Dementia
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چکیده
منابع مشابه
Brain Correlates of Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI)
BACKGROUND We recently reported that six alleles from class II genes of the Human Leukocyte Antigen (HLA) confer protection from Gulf War Illness (GWI) (Georgopoulos et al., 2015). The most significant effect is exerted on Neurological-Cognitive-Mood (NCM), Pain, and Fatigue symptoms, such that higher number of copies of the protective alleles are associated with lower symptom severity. Here we...
متن کاملReduced Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI)
BACKGROUND Gulf War Illness (GWI) is a disease of unknown etiology with symptoms suggesting the involvement of an immune process. Here we tested the hypothesis that Human Leukocyte Antigen (HLA) composition might differ between veterans with and without GWI. METHODS We identified 144 unique alleles of Class I and II HLA genes in 82 veterans (66 with and 16 without GWI). We tested the hypothes...
متن کاملP-145: Role of Human Leukocyte Antigen in Miscarriage
Background: During pregnancy, the maternal immune system is in close contact with cells and tissue from the semiallogenic fetus .The human leucocyte antigen (HLA) class Ib molecules, HLA-E, -F and -G, are expressed at the materno-fetal interface. Because of the apparent immunoregulatory functions of these proteins, they may be involved in successful acceptance of the semi-allogenic fetus during...
متن کاملHuman Leukocyte antigen-G (HLA-G) and gastrointestinal malignancy
Malignant conditions can affect any part of the gastrointestinal (GI) tract, including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus (1). Currently, conventional TNM staging is the most important prognostic factor for determining the clinical outcome of GI cancer. However, clinical studies have shown that patients with similar stages of the ...
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ژورنال
عنوان ژورنال: Journal of Neurology & Neuromedicine
سال: 2019
ISSN: 2572-942X
DOI: 10.29245/2572.942x/2019/1.1261